Supplements you can feel

We created JOYMODE to bring transparency, honesty, science, and premium ingredients to the ED supplement category. A category that’s always been sketchy, opaque, hard to trust, and at times dangerous. We only use science-backed ingredients that have been studied in human beings in peer reviewed studies. Every ingredient in each of our formulas is thoughtfully evaluated by our team of Doctors and PhDs and then sourced from premium suppliers. Thanks for giving this page a visit, and hopefully giving our products a try!

  • Formulated by doctors and PhDs

  • Science backed ingredients

  • Multiple peer reviewed in human studies on each ingredient

Created by doctors
Backed by science
Third-party tested
Supporting Research

Sexual Performance Booster

  • Arginine Nitrate

    Nitrate Ingestion: A review of the health and physical performance effectsWilliam T Clements, Sang-Rok Lee, and Richard J Bloomer Link

    Potential benefits of dietary nitrate ingestion in healthy and clinical populations: A brief reviewSinead T J McDonagh, Lee J Wylie, Christopher Thompson, Anni Vanhatalo, Andrew M Jones Link

  • L-Citrulline

    Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction. Luigi Cormio, Mario De Siati, Fabrizio Lorusso, Oscar Selvaggio, Lucia Mirabella, Francesca Sanguedolce, Giuseppe Carrieri. Link

    Oral L-citrulline supplementation improves erectile function in rats with acute arteriogenic erectile dysfunction. Arufumi Shiota, Yuji Hotta, Tomoya Kataoka, Masahiko Morita, Yasuhiro Maeda, Kazunori Kimura. Link

    Oral supplementation with a combination of L-citrulline and L-arginine rapidly increases plasma L-arginine concentration and enhances NO bioavailability. Masahiko Morita, Toshio Hayashi, Masayuki Ochiai, Morihiko Maeda, Tomoe Yamaguchi, Koichiro Ina Masafumi Kuzuya. Link

    L. Citrulline: a new player in the control of nitrogen homeostasis. Christophe Moinard, Luc Cynober. Link

    Treatment of erectile dysfunction with pycnogenol and L-arginine. R Stanislavov, V Nikolova. Link

    Oral L-citrulline and Transresveratrol Supplementation Improves Erectile Function in Men With Phosphodiesterase 5 Inhibitors: A Randomized, Double-Blind, Placebo-Controlled Crossover Pilot Study. Masato Shirai, Ippei Hiramatsu, Yusuke Aoki, Hirofumi Shimoyama, Taiki Mizuno , Taiji Nozaki, Shinichiro Fukuhara, Atsushi Iwasa, Shinji Kageyama, Akira Tsujimura. Link

  • Panax Ginseng

    Herbal dietary supplements for erectile dysfunction: A systematic review and meta-analysisFrancesca Borrelli, Cristiano Colalto, Domenico V Delfino, Marcello Iriti, and Angelo A Izzo Link

    Red ginseng for treating erectile dysfunction: a systematic reviewDai-Ja Jang, Myeong Soo Lee, Byung Cheul Shin, Young Cheoul Lee, and Edward Ernst Link

    What do most erectile dysfunction guidelines have in common? No evidence-based discussion or recommendation of heart-healthy lifestyle changes and/or Panax GinsengMark A Moyad and Kwangsung Park Link

  • Vitamin C

    Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies. Alan Mortensen, Jens Lykkesfeldt. Link

    Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. S Taddei, A Virdis, L Ghiadoni, A Magagna, A Salvetti. Link

    Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. F K Timimi, H H Ting, E A Haley, M A Roddy, P Ganz, M A Creager. Link

Testosterone Support Complex

  • KSM66 Ashwagandha

    Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study. Vijay R Ambiye, Deepak Langade, Swati Dongre, Pradnya Aptikar, Madhura Kulkarni, Atul Dongre. Link

    Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males. Mohammad Kaleem Ahmad, Abbas Ali Mahdi, Kamla Kant Shukla, Najmul Islam, Singh Rajender, Dama Madhukar, Satya Narain Shankhwar, Sohail Ahmad. Link

    Efficacy of Withania somnifera on seminal plasma metabolites of infertile males: a proton NMR study at 800 MHz. Ashish Gupta, Abbas Ali Mahdi, Kamla Kant Shukla, Mohammad Kaleem Ahmad, Navneeta Bansal, Pushplata Sankhwar, Satya Narain Sankhwar. Link

  • DIM

    Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation. P H Jellinck, P G Forkert, D S Riddick, A B Okey, J J Michnovicz, H L Bradlow. Link

    Attenuation of Carcinogenesis and the Mechanism Underlying by the Influence of Indole-3-carbinol and Its Metabolite 3,3'-Diindolylmethane: A Therapeutic Marvel. V L Maruthanila, J Poornima, S Mirunalini. Link

    3,3'-diindolylmethane modulates estrogen metabolism in patients with thyroid proliferative disease: a pilot study. Shilpi Rajoria, Robert Suriano, Perminder Singh Parmar, Yushan Lisa Wilson, Uchechukwu Megwalu,2 Augustine Moscatello, H. Leon Bradlow, Daniel W. Sepkovic, Jan Geliebter, Stimson P. Schantz, and Raj K. Tiwari. Link

    Chemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies. Cynthia A Thomson, Emily Ho, Meghan B Strom. Link

    3,3-Diindolylmethane (DIM): a nutritional intervention and its impact on breast density in healthy BRCA carriers. Rinat Yerushalmi, Sharon Bargil, Yaara Ber, Rachel Ozlavo, Tuval Sivan, Yael Rapson, Adi Pomerantz, Daliah Tsoref, Eran Sharon, Opher Caspi, Ahuvah Grubsrein , David Margel. Link

  • Magnesium

    The Interplay between Magnesium and Testosterone in Modulating Physical Function in Men. Marcello Maggio, Francesca De Vita, Fulvio Lauretani, Antonio Nouvenne, Tiziana Meschi, Andrea Ticinesi, Ligia J. Dominguez, Mario Barbagallo, Elisabetta Dall'Aglio, and Gian Paolo Ceda. Link

    Magnesium and anabolic hormones in older men. M. Maggio, G. P. Ceda, F. Lauretani, C. Cattabiani, E. Avantaggiato, S. Morganti, F. Ablondi, S. Bandinelli, L. J. Dominguez, M. Barbagallo, G. Paolisso, R. D. Semba, and L. Ferrucc. Link

  • Boron

    Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour. Link

    Nothing Boring About Boron. Lara Pizzorno. Link

  • Zinc

    Zinc status and serum testosterone levels of healthy adults. A S Prasad, C S Mantzoros, F W Beck, J W Hess, G J Brewer. Link

    Dietary zinc deficiency alters 5 alpha-reduction and aromatization of testosterone and androgen and estrogen receptors in rat liver. A S Om, K W Chung. Link

    Relationship between serum levels of testosterone, zinc and selenium in infertile males attending fertility clinic in Nnewi, south east Nigeria. A O Oluboyo, R U Adijeh, C C Onyenekwe, B O Oluboyo, T C Mbaeri, C N Odiegwu, G O Chukwuma, U F Onwuasoanya. Link

    Effect of fatiguing bicycle exercise on thyroid hormone and testosterone levels in sedentary males supplemented with oral zinc. Mehmet Kilic. Link

    Relationship between testosterone and erectile dysfunction. Jacob Rajfer Link

    Correlation between serum testosterone level and concentrations of copper and zinc in hair tissue. Chung Soo Chang, Jong Bo Choi, Hae Jin Kim, Sat Byul Park. Link

Sleep Support Complex

  • L-Theanine

    In search of a safe natural sleep aidTheertham P Rao, Motoko Ozeki, and Lekh Juneja Link

    Effects of L-Theanine administration on stress-related symptoms and cognitive functions in healthy adults: A randomized controlled trialShinsuke Hidese, Shintaro Ogawa, Miho Ota, Ikki Ishida, Zenta Yasukawa, Makoto Ozeki, and Hiroshi Kunugi Link

  • Melatonin

    Melatonin treatment for age-related insomniaI V Zhdanova, R J Wurtman, M M Regan, J A Taylor, J P Shi, and O U Leclair Link

    Optimal melatonin dose in older adults: A clinical review of the literatureMackenzie Pierce, Sunny A Linnebur, Scott M Pearson, and Danielle R Fixen Link

  • Magnesium Glycinate

    Association of Magnesium intake with sleep duration and sleep quality: findings from the CARDIA studyYijia Zhang, Cheng Chen, Liping Lu, Kristen L Knutson, Mercedes R Carnethon, Alyce D Fly, Juhua Luo, David M Haas, James M Shikany, and Ka Kahe Link

    The effect of Magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trialBehnood Abbasi, Masud Kimiagar, Khosro Sadeghniiat, Minoo M Shirazi, Mehdi Hedayati, and Bahram Rashidkhani Link

    Enhancement of learning and memory by elevating brain MagnesiumInna Slutski, Nashat Abumaria, Long-Jun Wu, Chao Huang, Ling Zhang, Bo Li, Xiang Zhao, Arvind Govindarajan, Ming-Gao Zhao, Min Zhuo, Susumu Tonegawa, and Guosong Liu Link

  • Tart Cherry Extract

    Nutritional interventions to improve sleep in team-sport athletes: A narrative reviewMadeleine Gratwicke, Kathleen H Miles, David B Pyne, Kate L Pumpa, and Brad Clark Link

    Pilot study of Tart Cherry juice for the treatment of insomnia and investigation of mechanismsJack N Losso, John W Finley, Namrata Karki, Ann G Liu, Weihong Pan, Alfredo Prudente, Russell Tipton, Ying Yu, and Frank L Greenway Link

Featured Products

Everything you need to get started with your sexual wellness journey